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With the annihilation of 32-bit application support under MacOS Catalina, MOO2 for Mac is slated for inoperability. Will there be 64-bit compatibility for MOO2?
Most likely there will arrive a compatible version soonish using 64 bit DOSBox but not working for GOG, I cannot promise you with certainity.
Try now as it should be updated.
I just tried to reinstall MOO1 in Catalina and it does not work. It says the installer needs to be updated because it cannot be scanned for viruses.

“master_of_orion_classic_enUS_1_0_33010.pkg” can’t be opened because Apple cannot check it for malicious software.
Delete your old installer and download the new one, IF it is new.