Gothic 1
Gothic 2
Day of the Tentacle
Lands of Lore 1
Zelda - A Link to the Past

1. Civilization IV
2. Swords of the Stars
3. Wasteland II
4. Railroad Tycoon 3
5. Tie Fighter

Amiga:

Another World
Dungeon Master
Fiendish Freddy's Big Top O' Fun
It Came From The Desert
Lemmings

PC:

Day Of The Tentacle
Full Throttle
The Journeyman Project 2: Buried in Time
Max Payne
Portal 2

Indie:

Braid
Cave Story
Super Meat Boy
VVVVVV
World Of Goo

Nintendo:

Chrono Trigger
EarthBound
The Legend Of Zelda: A Link To The Past
Super Mario World
Super Metroid

PlayStation:

Castlevania: Symphony Of The Night
Final Fantasy VII
Shadow Of The Colossus
Twisted Metal 2
Vagrant Story

Honorable mentions:

Blaster Master
Contra: Hard Corps
Heart Of Darkness
Indiana Jones And The Fate Of Atlantis
Lands Of Lore: The Throne Of Chaos
The Legend Of Zelda: Ocarina Of Time
Limbo
Mike Tyson's Punch-Out!!
Ni No Kuni: Wrath Of The White Witch
River City Ransom
Sam & Max Hit The Road
The Secret Of Monkey Island
Super Mario World 2: Yoshi's Island

Abe's Exoddus
Simon The Sorcerer 2
Metal Gear Solid
Resident Evil 3
Resident Evil 4

In no particular order...

Descent 2
Minecraft
Total Annihilation
Gran Turismo 6
One of the Ratchet & Clanks... maybe UYA?

I'd stack the R&C series as one game if I could. They're all great (except Deadlocked, that was weird)

I'd love to play that one day, but I don't have a console for it. I'll have to decide which is the best ito what else I can play on it first.
I found out about the game in Gametrailer's Castlevania Retrospective

Try a playstation emulator my friend. It works wonderfully.

Another of these, eh. Without thinking too much, and bulleted and not ordered:

* Deus Ex
* Final Fantasy Tactics
* Super Metroid
* Civilization 4
* Diablo 2

Honorable mentions (ie, next ones that came to mind quickly):
* Duke Nukem 3d
* Super Mario World

Okay, okay, EDIT: I erred egregiously by not including above:
* FTL

1. Eador: Genesis
this is by far the best game ever, huge gap in between




2. Imperialism series
3. Civilization series
4. Anstoss 3 (german football manager)
5. Sots: The Pit (did not think that I would love this game so much when I started it)

Unreal Tournament 2004
Guild Wars 1
Warcraft 3

These 3 games are on top for me without hesitation, but when it comes to 4th and 5th place, there are like 50 games I can't quickly choose from.

The game is currently available for purchase through the Xbox Live Store and the Playstation Network. The consoles that are compatible with it are:

Xbox 360
Xbox One (available via Xbox 360 backwards compatibility)
PSP/PS3/PS Vita (One purchase grants you the option to use the game in all those three consoles)

Out of those 5, 3 are previous generation consoles (Xbox 360, PSP, PS3) and 2 are handhelds (PSP, PS Vita).

Doom
Burger Time
Spelunky
Civilization 2
Metroid

Thanks for saying 1 and its joke of a "sequel". :)

I have considered it, but mostly because I want to play Dog's Life. It's such a wonderful but neglected premise for a game: just being a dog :P

1. Dishonored
2. RAGE
3. Beyond: Good and Evil
4. Mafia II
5. The Incredible Adventures of Van Helsing (well, all of them)