Tangledeep is easily one of the best roguelike games I've played, up there with the likes of Tales of Maj'Eyal, Caves of Qud, Brogue, and Dungeon Crawl Stone Soup. But if you're new to the genre that doesn't matter much. What you need to know is that this is probably the best place to start if you're interested in the roguelike genre.
First the aesthetics: it has fantastic 16-bit-like JRPG graphics in the style of Secret of Mana or Chrono Trigger. The music, which echoes that same era, is brilliant and even features music from Grant Kirkhope (Donkey Kong 64, Desktop Dungeons), Hiroki Kikuta (Secret of Mana, Soul Calibur V), and Norihiko Hibino (Metal Gear Solid 2, Metal Gear Solid 4, Bayonetta 2). And the atmosphere, which touches on the narrative a little, is an awesome mixture of playful and suspenseful, with environments that range from the beautiful to the imposing.
Next, the gameplay: the developers have gone way out of their way to make this as approachable and as fun to play as any JRPG you love. You can do it all with a mouse if you want. On top of that, they've removed many of the most annoying aspects of roguelike gaming. You know the ones: mystery items you have to use to identify, cursed weapons you can't remove without the right items, randomized enemy placement that puts 10th floor monsters on the first floor, and etc. Tangledeep is balanced, quick, and a ton of fun to play, with many of its systems out in the open. Stats, attributes, item descriptions, and tutorials are all in-game and super helpful. If previous roguelikes have intimidated you, start here. It'll help a ton.
Last, it's a ton, ton, ton of fun. There are multiple classes, tons of weapons, armor, and magic, summons, pet monsters, a casino, legendary item sets, and plenty of good humor. Plus there's a fun (though relatively small and straightforward) story here, which kept me engaged and endeared me to the characters.
TL;DR versio - PLAY THIS GAME! It's beautiful.