If you are a fan of isometric CRPGs but have always wanted them to be a little more grimdark, this is the perfect game for you. Whether you want to burn it all down for the glory of the God Emperor, revel in heretical nonsense, or try (and fail, but still try) to be a good person, Rogue Trader has you covered.
This is the closest I've ever come to a pen-and-paper resource management game, which is a compliment. If you enjoy paying close attention to your resources and the stress of not knowing if you'll make it to your next stop, this game will make you very pleased indeed. The storytelling elements are thoroughly enjoyable, and make for an imminently replayable adventure. I'm very impressed with their work, and would expect that many people who aren't necessarily fans of the play style will find that they enjoy this game more than they anticipated.