Great game, still holds up magnificently after all these years. As others have said, get the mouse fix but do still expect the mouse to be a little bit unwieldy. It's not too much of a problem, but can be an issue in some specific areas (shooting the turret, shooting while being dragged). Also, when you're jumping in Zero-G, try to make sure your trajectory is as perpendicular to the landing surface as possible. If you're too close to being parallel, Isaac will freeze in midair and spontaneously die. Really annoying. Other than that, though, phenomenal game. The story is good, if not a little predictable, the atmosphere is lovely, and the graphics have held up surprisingly well considering they're 12 years old. At the very least, a solid 5 hours of quality entertainment.