The best away to play this mod is to set up the gameplay style to Biomod in the settings. This grant a new experience in not only the maps but the gameplay will change as well. Some changes such as having a bio canister for an already installed aug will be treated as an upgrade by the med bot, drone at level 4 can interact with objects and hack terminals, special weapons like Paul's baton to knock mibs and commandos if you play non-lethal.
The ragdoll physics are fun, but the style of the game feels more star trek than cyber punk. Story gets a interesting once you pass Egypt. This does have multiple endings but only one I found satisfying. There is a load screen issue but it can be fixed by getting the all in one fix mod. The tranq rifle requires multiple shots to take down an enemy non lethal. This is significantly easier than the first. Overall story is ok and gameplay is still enjoyable.