The MacOS "support" is a sham. The game always runs at your native display resolution; in my case 3360 × 2100. You CANNOT change this. I have a fairly recent 15'' macbook pro with a dedicated GPU (Radeon Pro 460 4GB), and the game has a terrible framerate _in the menu_. Don't let "indie" 2D graphics fool you. This game is a performance hog, requires a dedicated GPU, and is NOT playable on a macbook.
Third Tim Schafer game I played and didn't like. The high rating and rapt reviews are due to a self-selection bias. A regular gamer reading this is unlikely to be in the target audience. If you don't already love point-and-click adventures, don't bother. The quirky aesthetic is "lolrandom" and superficial; this bland "good bad boy" story might as well be set in 1960's New York. The inventory UI is infuriatingly slow for "artsy" reasons. Too many puzzles are unlogical; you will reach for a walkthrough and gain no satisfaction, or spend hours in frustration. Too much busywalking from place to place. If the above doesn't dissuade you, congratulations and have fun.