On inital launch, nothing happened. Went to the game directory and launched from there, recieved an error message "iwd2.exe the application was unable to start correctly (0xc0000022)". This is due to windows 10 not natively having directplay installed, as its really old. After installing that through the control panel >Programs and Featuers > Turn Windows features on or off > Legacy Components - DirectPlay, the game ran. Gog have bundled a ddraw/wine emulator thing for some compatibility issues, this is located in the same folder as your iw2.exe, you can use this to change emulation types. The one they default too will give you slightly longer load times but has the best mouse movenment. if the load times bother you, you can change it with the setup-ddrawfix.exe.