Hello,
I have problem, when i'm playing game is shutting down sometimes after 2 min, 5 min and sometimes after 40 min,
There are no communication about problems, it just crashing.

https://www.youtube.com/watch?v=u6tALhoKZ0g

I am having the same problem - it crashes after a random time with no warning and no detail as to what has happened?
I have a Ryzen 2400G with a dedicated graphics card 1660ti ....
Any ideas anyone??

There's a bunch of possible reasons for the crashes. Perhaps you'll find the solution here:

https://support.gog.com/hc/en-us/articles/213040145-Crash-to-desktop

https://steamcommunity.com/app/292030/discussions/0/133257324788833004/

https://wbgamessupport.wbgames.com/hc/en-us/articles/360001119428-The-Witcher-3-Wild-Hunt-is-crashing-on-my-PC

https://levelskip.com/rpgs/How-to-fix-crashes-in-The-Witcher-3-and-improve-performance

Problem has been solved, it was fault of mods which i had installed Have you installed any additional fan mods? try to uninstall them it helped me

Thanks for the reply, but I do not have any unofficial mods installed. Will try the other options and see what happens.

Well, after a look around - I decided to roll back the NVidia driver to 425.31 from 430.x and I have stable gameplay and no BSOD's. So I'll keep this for the moment and update when NVidia come out with a newer driver.
All the best

After a few hours of painfree gameplay, I have restarted my machine today - and as far as I know, nothing has changed but the Witcher 3 just crashes AGAIN! and AGAIN!
This is so frustrating .... anyon have a long lasting solution to this?

The solution I have found is to NOT run the game via the GOG Galaxy program - if I do, it crashes -if I don't it works fine.