ltron: I have the same problem with an r9 390x and a core I7 5820k. The game was running perfectly with patch 1.22 and driver 16.7.2. I updated to 16.8.2 and that introduced some annoying stutter and then patch 1.30 made it significantly worse.

I'd recommend verifying the game files in manage installation and if that doesn't work try 16.7.2. If this still doesn't help we'll just have wait until they fix it.

ltron: Have you tried driver 16.8.3 released today? This driver seems to have improved things for me quite significantly.