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I wanted to play The Witcher, so I bought it from and then I bought it again from GOG as I hate the DRM system.
On my Intel HD 2500 (i5-3470 CPU integrated) video card I could not play it so I bought a low profile Sapphire Radeon HD 7750 1GB DDR5 video card. What are the best settings for the game when used with this video card? My monitor supports 1600x900
I am asking this because I still see delays.

I can't tell you about this specific card, but for comparison: I'm currently playing this on a Geforce 430 GT which has 512 MB of VRAM, and my settings are at "High" on 1650*1080. Runs smoothly, though I think I set the AA to 2. With this, not even the swamp made problems (loads of anti-aliased trees). I don't know about Chapter III - haven't been there yet. The 7750 should be faster than the 430, so you should be able to run it on "High" settings.