I have an i7 with whatever 70 million cores, and a 560ti graphics card, running Win7 64bit.
It works! I had it at 1680 x 1050, it looked great, played smooth and oh its Startopia!! I only played for a short while tho, so can not vouch for bigger stations and more action.
I have the original discs but its a pain, this wasn't. Not claiming it will be perfect for everyone, but it was for me.