PLMike: User SemiShade posted a solution in this topic: "SoF will not launch" 
 Quote: 
 "I got it up and running just fine. Note that I am running the lastest version of Windows 10 x64. Here are the steps that I had to take in order to make it work properly:  
 1.) Install SoF 
 2.) Install SoF Plus to your Soldier of Fortune directory 
 3.) Make a copy of the SoF execuable (SoF.exe) 
 4.) Rename the copied SoF.exe to mohaa.exe 
 5.) Run SoF from the mohaa.exe for now on  
 I sent the mohaa.exe to my desktop and renamed it SoF and it works just fine for me."  
 I have Windows 11 x64 and this solution worked for me.