I am running PG2 in Windows 7 Ultimate with 2 monitors. When I move the mouse to the right or side of the screen the screen doesn't scroll to the right and I've got to fiddle with trying to find a spot right on the edge just before I move to the second monitor.

Is there a way to run this title so that it isn't in windowed mode?

I'm running into the same problem with other games. I don't have a solution though.

The problem is that PG2 predates Win98 so there was no way for them to know that multiple monitors might be a problem in the future.