Any hopes of a Mac OS X version running through Wine? Similar to the ports of Fallout and Sniper Elite: Berlin 1945?
I have something that may work for you. I got Nosferatu to run on my Macbook Air (early 2014). I'm running OS X 10.10.4. Intel Core i5.
I used Wineskin with Wine version 1.3.19. No winetricks or other stuff to install.
Just create a new wrapper with that version and install the .exe for Nosferatu. You will get some errors at the end of the installation. Just click them away. The first time you run it, it may hang on a black screen for about 20 or 30 seconds, but it will resolve itself and then run just fine. I have played it for about an hour now, and it runs great. It automatically runs on full screen, too.
It is a really cool game, with some creepy atmosphere, and decent scares. Good luck running it on your Mac. Hope this helps!