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Now, it took me quite awhile (loads of internet searches + trial and error) to figure this out, so I wanted to share it in case anyone else has the same issue. M&M VI + VII absolutely work on the mac!

M&M VI:
I got this working with Wineskin - the trick here is the install the game using the Wrapper version: 2.5.8, and the engine: WS9Wine 1.5.10NoXInput2. Also, in "wineskin advanced -> set screen options" you have to choose "override" and set fullscreen to 640*480.
*NOTE* for some strange reason the game starts with major flickering issues, however these can be relieved by clicking the mouse before the 3DO logo appears. No joke!

M&M VII
Same story...game runs perfect when installed with Wineskin 2.5.9, using the WS9Wine 1.5.10NoXInput2 engine. For some reason this does not flicker at all, thus no clicking required!

enjoy these games. Hope it helps.