Last part of Chapter 14 I have the cash to take to Bruno the money lender, but after the cutscene, I've hit an infinite loading screen and can't progress to Chapter 15. Only thing I can do is CTRL+ALT+DELETE to get out of the game, same problem every time and can't progress any further at all.

Doing a little digging I found some old threads on the TAKE2 forums, with the same problem not long after the game was initially released. Poor show if it's never been fixed and as yet, I've found no workaround or fix anywhere online.