I hit play, the screen goes black for a few seconds and then crashes to the desktop with no notification or popup.

Details:
Windows 10 Professional.
I have no joysticks/gamepads attached.
Windows XP compatibility mode and administrator mode do nothing.
I've tried launching larry.exe manually, just in case some launcher was causing fits and nothing.

I hate crashing to desktop. If I had an error code or dialog, I'd at least have something to work with, but this is giving me nothing. Any ideas?