phase.verocity: I managed to get it working. look for these two video's on the net
Kings Quest: Mask of Eternity - Install Part 1
Kings Quest: Mask of Eternity - Install Part 2
after that set the compatibility to windows xp service pack 2.
After that it ran but I crashed if i tried to pay the intro movie.
might be your graphic card Nvidia vs your processor. Try setting your graphic card inn your settings to run on either your processor or on your graphic card processor only. Some games have trouble if the workload is split.
second maybe your processor in general. Turn down the amount of cores that are being used. This works for instance with tombraider with startup problems.