This is basically just an FYI. I have a home desktop where I run the game at 4k resolution. I also occasionally play on my laptop at 1080p. The Cloud save feature is great for just continuing the same game, but it also syncs the game.ini file that in the same documents folder as the save files. If the game is set to launch at a higher resolution than your display supports, it will simply fail.

If you have failure to launch and you use Cloud saves, this may be a possible cause.