Sorry for Necroposting, but I have another tip and I didn't want to start a new thread.
It's a spoiler too, so beware.
Many people have really big problem with one of the first bosses in game - the mother with her childrens. When you kill one of her offspring, she starts going medieval on your sorry hides. The actual trick is to NOT kill the children before you kill her - they're pretty harmless (compared to their mom, anyway), and she don't use her venom attack that way, making her pretty docile opponent.
Actually, there is much more funny tactics that you can discover in this game. The actual puzzles are not those about using item to gain something, as they're pretty obvious, but those that involves using your enviroment during combat for your advantage. Remember, you can push boxes, sometimes blocking your enemies and rendering them defenseles.
Post edited August 02, 2011 by wolfy85