ajallan: I pretty much am looking for any isometric rpgs that are not strictly turn-based (like Fallout, Jagged Alliance, etc.).
Apart from the ones that have been mentioned already ...
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Nox: an Action RPG but not random and more story-oriented than Diablo; after years and years I'm still struggling to motivate me enough to complete Diablo 2 - never had that problem with Nox. It also has significant replay value because as far as I remember different classes get to explore different areas of the game (available here on GOG.)
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Rage of Mages &
Rage of Mages 2: Necromancer: A blend of RPG and RTS, but the only one that ever worked for me - I actually kind of dislike RTS, but I enjoyed this series. There are no building phases or the like, it's just that the maps and the combat are similar to RTS games. (Currently not available as digital download though, AFAIK.)
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Revenant: Another story-oriented Action RPG without the random parts, although admittedly it has less story than Nox and Divine Divinity and is quite linear. Probably not your first choice, but I liked it anyway. (Currently not available as digital download though, AFAIK.)
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Lionheart - Legacy of the Crusader: I haven't played it myself yet but it sounds comparable to Divine Divinity in that it is a story-oriented Action RPG with roleplay elements that is said to be interesting during the first half and gets more and more hack-and-slashy and boring towards the ending (available here on GOG.)
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Silver: another linear Action RPG with a JRPG touch but real-time combat; a fun game, but I'm not sure it's what you're looking for (available here on GOG). (Not sure if this counts as isometric, but as far as I remember at least the backgrounds are static like in BG.)
All others I can think of are turn-based (Avadon, Geneforge, Avernum, Albion, The Temple of Elemental Evil ...) or 3D - although technically Neverwinter Nights is not isometric either, so you might still be interested in NWN2 (available from other digital distributors with DRM) or Vampire The Masquerade Redemption (available her on GOG).