Worms Reloaded. There was a time when I didn't play anything else, but still bought new games from time to time. The backlog got bigger and bigger, but I still played pretty much only Worms. After 1200+ multiplayer victories and 666 hours clocked in, I forced myself to stop. Two things helped: first of all the number of clocked hours is pretty wicked as is so therefor I don't want to mess it up, and Worms Revolution beta was a nice way to gradually remove the addiction. Now I haven't played any Worms titles for about two, maybe three months (haven't played Reloaded for about 5-6 months), and in that time I have massively reduced my backlog.
Currently I only have two must-play-and-finish games in my library left, Icewind Dale 2 (I'm on chapter 2 at the moment), and Gemini Rue (haven't started yet). After I've beaten those, I might move on to Sacrifice, or maybe The Witcher. What I mean is, there is a small bunch of other worthy games too besides the two I mentioned, but they aren't at the top of my list of games I own and want to finish someday too. Also, there's a huge amount of crap on my Steam library, mostly because of different indie packs, but I don't think I'm going to ever even try some of them. I'm really happy about my current situation, and how I was able to move on to other games I wanted to play and finish; and especially happy about how my backlog is now a very fraction of what it once was. Remember kids, don't do drugs and Worms titles.