Since you played Icewind Dale 2, you might want to try Baldur's Gate 1&2 and Icewind Dale 1.

Who is explicitly genderless.

Another vote for Dark Souls. It's pretty unforgiving towards new players, but if you find it daunting, the Extra Punctuation article (or some such one-pager) should give you enough of a boost to get started. Definitely helped me, and I would rank DS high among my favourite games of all time.

The original Dark Souls had awful KB+Mouse controls though, so I've just stuck with a controller. Not sure whether the controls were improved for the sequels or the Remastered edition of the original.

Darksiders 3

Bloodstained

Dragon Age: Origins my favorite RPG!

Had another look at the list of games you have played; the first time I just had a quick skim through and somehow missed the fact that my favourite game, Planescape:Torment, is not on it. The protagonist is always male, but the game is stocked with interesting characters (female, male and non-gendered) that it shouldn't really matter.

Speaking of favourite games and the list... I see Neverwinter Nights 2 there, so I have to ask whether you played Mask of the Betrayer as well. If you haven't, you know what to do.

You have great taste in games, by the way!

Elder Scrolls IV: Oblivion
Shadow Tactics
Victor Vran
Dragon Age: Origins

The Incredible Adventures of Van Helsing

Also i spent some time in Spiral Knights and usually recommend it if somebody ask) (Free game)

Since you mentioned Divinity: Original Sin 2, it might be worth moving backwards in the series a bit. The first one is also quite good, and I actually prefer the combat (previous to the new armor system). The story is more wacky, though. The soundrack is awesome, and helped me push past the first town (perhaps the slowest point of the game). If you like exploration and good music with a focus on turn-based combat, this one is a lot of fun.

Divinity 2 Developer's Cut is also worth a look. You play in third-person with a singular hero, which can be female. You can build the hero however you wish, through skill trees and attribute points. It has a lot of humor, especially through the Mindreading ability. Your hero gets a...special ability, as well, which sets her apart from the crowd. The graphics still hold up well, as well as the music. It is more of an action-RPG, focused on your individual hero fighting groups of enemies, but with a good balance of dialogue and plot alongside the action. There are also a few decisions which allow a second playthrough to have some differences.

Since you mentioned Neverwinter Nights 2, I would say Dragon Age: Origins is worth a mention. The story is good, the recruitable NPCs are interesting, and you can most certainly play a female (or even a dwarf). There are many dialogue choices, and since the PC isn't voiced (similar to NWN), you can ascribe whatever personality you see fit. These choices also make it have good multiple-playthrough potential.