The Dracula trilogy and 4+5 are FPS games like Myst and if you want a 3rd person type there is Gabriel knight 3 or the moment of silence but I would wait for a sale for some of those games.

What are these RHEM games? The 7th guest isn't on GoG anymore and some of the sherlock holmes games have slight graphics issues on Nvidia cards like Sherlocks glow in the dark Watson.

No need to use Steam if you don't want to. Humble Store has Haven Moon and itch.io has Eyes of Ara, both DRM-free.

They are 1st person puzzle adventure games in style similar to Myst. So far 4 have been released.
Each one takes place in a different section of a huge place called RHEM; a labyrinth-like place (with outdoors and indoors sceneries, underground caves, industrial settings and many more) full of perfectly designed mind-bending puzzles. Everything you see as you wander around may actually be part of a puzzle.
Each of these is a full-length standalone game (I remember spending at least 20+ hours in each one) and you don't need to play them in any particular order as there is no substantial plot to follow (the plot is that you are called to retrieve some artifacts for someone - really, that's about it).
In my opinion, if you liked the Myst series you should totally check out RHEM (I ended up liking the latter much more that the former; the only strong point of Myst over RHEM is the story).

RHEM website

Have you played all of the Myst Series games?
I think there are 8 or 9 of them
ei. : Riven, Myst Masterpiece, Myst URU, etc...

Obduction
JULIA
Nibiru
Aura

Kinda not quite Myst-like, but still alot of puzzles:
Tunguska
Corrosion: Cold Winter
7th Guest
11th Hour

In a different style, there's the "The Room" series. It's guess-how-the-machinery-works puzzles, but focused on weird puzzle boxes, that you can fully rotate in 3D.

Ah, memory lane...
The Light House was the first puzzle adventure I played.
They were sold out of Myst at the time.

The Schizm series required you to be a Menza member to solve
many of the puzzles, unless... you had a walkthrough(gasp)

Not a weird suggestion. I had actually added that one to my list already :) It looks up my alley I really enjoyed Timelapse. Thank you. And broke down and created a Steam account since i could be here a while and need more options. Haven Moon was great too. I think I wound up adding most if not all you recommended here. They look like the kind of games I'd enjoy. Thanks for all the great recs.
Added most of those to my list. Thanks! (I did add the Dark Fall series to my list, but they're not high up... horror/ghost stories aren't as much my thing because I play in the middle of the night in an old house that makes noises on its own and despite living in this house 30 years, those noises still get to me in the dark lol)
They look perfect. I created a Steam account and found 3 of the 4 there.

Zork Nemesis and Zork Grand Inquisitor

also Amerzone

I've gotten about halfway through Return to Zork and really enjoy it. I'll definitely be playing the rest of the series. Amerzone looks great too!

I think the best choice would be the Journey Man Trilogy, which are games about a time traveling police man basically, which I found to be an awesome setting. Even though these games play like Myst, you can unfortunately die in these which might deter you. If it doesn't though, I'd say the puzzles are satisfying and, most importantly, the world feels absolutely real and immersed me in seconds. I would really, really recommend these to you, I think they are a great way to get your mind away from the pain.

Personally, I am currently playing a game called Lost Eden which is a first-person adventure game, but not exactly like Myst (since the puzzles are much easier). I think its music and interesting setting would be a good way to get you to forget about the pain, but it is an easy game that you will probably finish in no time (like three or four hours, from what I have heard). Still, this would be a feel-good snack!

If you are in the mood for darker and downright eerie stuff (which I wouldn't be if I was in pain), I'd recommend the Dark Fall games... Though I only played the first for a few hours, so I don't know if all the games in that series are good.

If you are looking for more fantastical stuff though, the Atlantis games and Schizm may be for you. Haven't played them myself, but my aunt swears by the Atlantis games and I have seen positive reviews of Schizm.

Nemesis is the most Myst-like I think because it has you exploring this deserted castle and doing a ton of puzzles. Grand Inquisitor is similar too, but more humorous and with more interaction with other characters. They're more myst-like than Return to Zork so if you like Return to Zork and you like Myst then I'm pretty sure you'll like Nemesis and Grand Inquisitor too.