Judging from the trajectory of his rep, I believe people are forgetting to +1 bler's helpful posts, such as the one above. Let's help him get to 150 before this game ends.

Big Jim Slade in Study with Pipe Wrench.

I'am confused with all these combos and to remember those which were already used ^^

Kane in Ballroom with Scissors.

Agent 47 in Conservatory with Pipe Wrench

Agent 47 in the ballroom with a pipe wrench

Guess #72:
Carlo Falcone in Study with Crowbar

Carlo Falcone in Lounge with Scissors

Mankar Camoran in Billiard Room with Hammer.

Carlo Falcone in Ballroom with Scissors

Agent 47 in Conservatory with Sword

Challus Mercer in the Dining Room with the Fire Poker!

Guess #73:
Jon Irenicus in Billiard Room with Meat Cleaver

Agent 47 / ballroom / pickaxe

Out for a bit.

Here come the clues
 
 
Suspect

 ▪  The murderer still has his/her jaw.
 ▪  The murderer doesn't wear a hat.
 ▪  The murderer doesn't wear glasses.
 ▪  The murderer is an adult.
 ▪  The murderer doesn't wear an eyepatch.
 ▪  You won't find the murderer in Arkham City.
 ▪  Lara Croft has never met the murderer.
 ▪  The murderer is not holding a gun.
 
 
Weapon

 ▪  The weapon doesn't require arrows.
 ▪  The weapon doesn't need petrol to be effective.
 ▪  The weapon is not typically used to hit a ball.
 ▪  The weapon doesn't use bullets or shells.
 ▪  The weapon doesn't have any electronic parts.
 ▪  Other weapons have names starting with the same letter.
 ▪  The weapon doesn't appear twice on the clue's picture.
 ▪  The weapon has at least one metalic part.
 
 
Location

 ▪  You can't access the restrooms from that location.
 ▪  No door leads to the water fountain.
 ▪  You can't park a car here.
 ▪  You don't need an umbrella when it's raining.  ( Note:  The front porch is covered )
 ▪  It's not a hallway.
 ▪  It's a room with at least one window.
 ▪  There is no locked door in this room.
 ▪  It's a room with two or three windows.
 
 
Guesses

 ▪  <span class="bold">All guesses in PDF format</span>  (Posts 1 - 612)

Hooray, Hitman exonerated :)
Jon Irenicus in Ballroom with Pickaxe