I don't recall the details of the game, but when it was fresh in my memory I posted this on another forum:
Rogues are useful in Buck Rogers, both for backstabbing and for their skills. Actually they are more useful than in the fantasy games, since they don't need to be dual classed to be useful. One is enough though.
One Rocket Jock is enough, but two Medics may be useful. An Engineer is also very useful.
I completed the game with the following party:
Terran Rocket Jock
Desert Runner Warrior
Tinker Medic
Martian Medic
Venusian Rogue
Venusian Engineer
In the long run, if you plan on importing the party to Matrix Cubed, replacing one of the Medics with a Warrior will be better.
I found that high STR is more important in Buck Rogers than in the other GB games. There are no spells or items to increase it, and you need pretty high STR to be able to carry heavy armour and weapons and be able to move unencumbered.
Also note that there are no opportunity attack rules, which means all characters and monsters can move freely.