Just downloaded fallout 4 from GOG to play fallout london, but when i get to the main menu my keyboard and mouse stop working, tried redownloading, turning bGamepadEnable to 0 and turning off all overlays like suggested in some posts 9 years ago, but nothing works. is there any other new fix for this?

I am having the same issue, a fix would be highly appreciated. Thanks!

Do you guys have a controller connected? Use it to turn off the controller in the options and you can use mouse and keyboard after settings are saved.

What is the brand of keyboard and mouse you are using?

This.

I read a post like that in Reddit. The guy latter got back that he had a controller plugged in and out of sight.

KB/Mouse will not work with controller plugged in.