blakjewellio: edit; ok if you launch from fallout 4 launcher it works
blakjewellio, That fails for me but in another way.
If I run it from the GOTY FO4 launcher FO-Lon appears to start and run OK carrying on from where I was save file wise. But it fails in other ways, like when I try to trade with Nadia I get a white box pop up that says something like 'F4SE is not running' restart the game' (or similar).
So it seems I can also start the game via the FO4 launcher but it just fails for me elsewhere.
If I try to start if from the Galaxy launcher it still fails with a flashing cursor then nothing.