Game does not start on a Atom powered Netbook in Win98 compatibility mode. A crash log in the program folder shows the following:
Location: 00415ab0
Reason: Access violation
Tried to read from memory location: 0x017b5000
Register dump:
EAX: 0x0000006c
EBX: 0x00000040
ECX: 0x00000009
EDX: 0x017b4fb8
EDI: 0x007ce318
ESI: 0x017b5000
EBP: 0x010cf5a0
ESP: 0x010cf590
EIP: 0x00415ab0
Floating point details:
Control word: 0xffff0e7f
Status word: 0xffff0020
ST(0): 30f1010f00f4f90e2cf1
ST(1): 8610806d00f4f90e0820
ST(2): 2cf1010f1ceaef0effff
ST(3): 0048fd03114eeee4fd3f
ST(4): 00000000904a7ef10040
ST(5): 0000000000000080fe3f
ST(6): 00000000904a7ed10140
ST(7): 0000000000000080ff3f
Stack dump:
007ce2d0
00000000
00000000
00134a80
010cf5f4
6de04cbc
017b4fb8
I think this is nothing which you GOG.com guys could change, though ...

Okay ... it is an issue with admin/non-admin control. If run with "run as" from a normal account, it won't recognize the compatibility selection. Thus you have to start it once from a full admin account, to be able to start it with "run as" from a restricted account.
(I noticed that the game looks somewhat unpolished ...)