I was in the mood for a platformer to play on my netbook (asus1000he), and after trying Bionic Commando: rearmed (no good for my hardware), I found this.
It works great. It does not have support for the native resolution 1024x600, however I was able to get that working by editing the config.cfg file to change the resolution, changing the shortcut to point to prism3d.exe instead of dukenukemmp.exe, and changing it to run as administrator (i'm using win7).
It appears to work perfectly in the widescreen mode, without distortion. It runs beautifully on my netbook and I am having FUN.