So, I changed dosbox to see my roland 32 emulator cause I think it has the best sound. However, this is the first game to ask me for interrupts and addresses. I don't have the patience to try them all, and went with the highlighted defaults. They didn't work. Does anyone know what to set this to to avoid this error -32 in module 5 message I'm getting.

What is your emulator? I assume MUNT. If not, please let me know what emulator (or an actual MT-32) you are using.

I believe the default that works in most DOS games is port 330, IRQ2, some games list it as 330h, which I believe is also the default.

Also, you may want to check your .conf file for Dragonsphere and get acquainted with it. The install of DOSBox that comes with the game will read that, and I am not sure the setup/install program will write to it for you.

I use MUNT too but, even if it doesn't work, it'll just be mute and not give that error. That error seems like it's related to the game not finding the mounted CD image. Are you starting it with the dosbox.conf that comes with the installer? Make sure the CD image is mounted inside Dosbox.