Tried to refresh memory before getting DOS V2

Just a cursor on black screen and nothing else and GOG-s "now playing..." popup

W10 up to date
Res is 1680x1050, tried 1280x768
R270 card
uninstalled - reinstalled C++ redistr 2012, 2013
uninstalled - reinstalled game
started exe with admin rights
no extra antivirus, just defender

what else?

https://www.gog.com/forum/divinity_series/divinity_original_sin_crash_at_startup_win_10/post2

Especially try deleting the "Divinity Original Sin Enhanced Edition" subfolder in "...\Documents\Larian Studios".