Is it crashing, or just not starting?

Are you shutting down all non-essential programs (especially anti-virus) before trying to start the game?

In the '..\Beyond Divinity\Static' install folder, try renaming the intro.mpg video (you can watch it in Windows Media Player, etc). That can avoid crashes with the game on startup.

In the 'Beyond Divinity' folder, try running the configtool.exe program directly, by right clicking and running as administrator. Once you click on the 'Apply & Close' button, that should start the game (there may be a bit of a delay).

You can also try starting the game directly from the div.exe executable. Right click, select Properties, switch to the Compatibility tab, and set it to run in a compatibility mode (Win9x, or XP, etc). You can also set it to always run as administrator, and 'disable display scaling on high DPI settings'

Check if there are files called debug.lst or error.txt in the Beyond Divinity folder. If so, what are the contents?

Try setting your desktop resolution and game resolution to be the same. At least with the disk version of the game, this helped a few people with crashes on startup (it minimizes DirectX's resolution switching).

Try downloading these configuration files and extracting them into your 'Beyond Divinity' install folder. They are from the disk version, but I don't think that should be an issue.

Do you have any video filters installed? With the original disk version the ReClock DirectShow Filter caused a conflict with the game videos, but I don't know if that is still the case (site doesn't exist at the old link I have).

Try verifying local files, if you are using the Galaxy client: select the game in the left column, then click on the More button, and in the Manage menu select 'Verify / Repair'.

Check for updated graphics drivers and Windows updates in general.
Try reinstalling the MS VC resistributable from the '..\Beyond Divinity\support\VCRedist' folder and reboot.

If you check the Event Viewer, does that give an error code or 'Faulting Module' file name that might help identify the cause of the crash?
- click Start (or WinKey-R), then type "event viewer" into the search box. in Windows 10, 'event' should bring up 'View event logs'.
- after starting the Event Viewer, expand 'Windows Logs' in the left column and select 'Application'
- in the center column, look for a recent error (maybe sort by Date and Time) for the game
- check the information under the 'General' tab below the list of events, starting with "Faulting application name..."