Well, as anyone who just purchased the above can tell you, it simply doesn't launch at all if your monitor is natively above a 1080p resolution.

There is a crash fix regarding the STEAM version. Does it work here? Yes, it does.

To to make a TL;DR of their convoluted solution:

1. Download any hex editor, but preferably the portable version of HxD. https://mh-nexus.de/en/downloads.php?product=HxD20

2. Open said hex editor. Drag-and-drop the DevilMayCry4SpecialEdition.exe file from the game folder to hex editor window. Or press Ctrl+O and use that to open the file.

3. Go to offset (Ctrl+G): 6790E7 (or 6787303 in decimal mode). You'll see the following hex values at cursor position: 80 02 00 00

4. Change that value according to your display's native resolution
1280xAny and above: 00 05 00 00
1360xAny and above: 50 05 00 00
1440xAny and above: A0 05 00 00
1600xAny and above: 40 06 00 00
1920xAny and above: 80 07 00 00
2560xAny and above: 00 0A 00 00
3840xAny and above: 00 0F 00 00
Save via Ctrl+S

5. The final step is to edit the config.ini with a text editor found at %LOCALAPPDATA%\CAPCOM\DEVILMAYCRY4SPECIALEDITION\config.ini

In that file, the resolution will say unknown. Simply insert your correct resolution, and the game works.

THANKS ALOT GOG! SOME REAL FINE WORK YOU PUT INTO THIS DISASTER! SMDH I'd hate to think of what shitty hardware you guys use to test stuff in order to make this glaring oversight and verify it as good. lmao@GOG

How GOG the game is advertised:

"This is the best version of this game you can buy on any PC platform."
"We are the only platform to provide tech support for the games we sell. If some issues with the game appear, our Tech Support will help you solve them."
"1.0 GOG changelog (18 June 2025):
Validated stability.
Verified compatibility with Windows 10 and 11."

In reality, it's up to the user to fiddle around with a hex editor to get the game to run at all, no thanks.
Actually, the non-working steam version is sold as GOG.

Agreed. Fuck GOG!

Works fine for me with 1440p screen, both Steam and GOG version.

Confirmed as working! Thanks for the update!

I play at 1440p at 120fps no problem. Never had problems with this game luckily.