I had played the game a lot until I decided to unistal both it and Galaxy for a few months until I finish college. When I installed again, another game I was playing (40K Mechanicum) loaded well, but Deus Ex keeps crashing unless it's on safe mode, and even them, I can see some visual glitches. Any way to solve it?

Try one of the many Deus Ex launchers. There's one primary one that most people use to get Deus Ex running.

(Though at this point, a remaster would be nice, since Deus Ex was made back in the 3DfX days.)

You should provide more information about your system (hardware, OS, etc.) in order to get help.

Have you tried launching it from the game executable without using Galaxy? Are you getting any error message when the game crashes? Have you read the log file (\Deus Ex\system\deusex.log)?

I'm using win 10, my processor is an AMD Ryzen 3 4300GE
Yes, I tried, the executable crashes the same. No, no error messages. I've read the log, but I got 0 knowledge in what exactly I should check on it.

What I should check in the log, btw?

I'm not sure, any useful information about the crash, I suppose.

That said, you could try installing Deus Exe and a Direct3D 10 renderer.

So, I tried, the Exe opens, but with lots of visual glitches, while the renderer don't work at all, it opens the game and it crashes again, without any error message, again.
Guess my PC decided I won't play the game no matter what I do, and I'm already deep into the game, I don't think I would start a new file if that's the problem.
I've saved the log, in this mediafire download, not sure what can be found of useful from here
https://www.mediafire.com/file/utdj3ihrd2nbpbs/Detected.log/file

There are other renderers you can try, such as this one or this one. Was this log created when the game started or when it crashed?
Anyway I can't see any error in the log but I see a problem: you installed the game in the protected "Program Files" folder. This is probably not the cause of the issues with the game, but should still be avoided.

No idea when the log was created, it showed up with the "detected" after i tried to unistal and instal again to see if it was the problem.

Tried the renderers, none work.

I'm convinced my pc just hates the game, there's no other explanation, it's running The Witcher 3 without a problem, but can't open Deus Ex anymore.

At least gonna try get the save file and store somewhere for a while, I'm not playing 18 hours again

Ok, the Kentie executable worked this time, not sure why it didn't the first time I tried.

Still, I really wanted to know why the game just bricced from nowhere.

Who knows. There could be an combinatorial explosion of reasons, or a simple singular one.