A couple of people are writing impolite things, trying to argue that cyberpunk is always sad and unpleasant. I would disagree with that.
Bladerunner was not an overall happy movie, granted, but it was not all that sad either. It was grim, but it was not about existential angst and despair over the futility of life. Same with Johnny Mnemonic, it was dark without pushing viewers into despair. Altered Carbon, extremely dark franchise, but Tak never lays down to die and if anything his achievements come down to aggressive perseverence and a fanatic refusal to give up hope. When he finally does sort of give up, in book 3, he sets himself a new mission that is no less ambitious.
How about the Judge Dredd franchise? RoboCop?
It is a core element in the genre that the setting is dystopian, but that does not force the story to be nothing but doom and gloom, and indeed most of the stories contain some positive messages and happiness here and there. It is dark, but it is not eternal blackness.
Now consider the story of this game, and yes, spoilers ahead.
V comes to Night City for a fresh start and a shot at life. We know that Jackie's goal is to be a legend, but we don't really know what V's goal is. And we don't really get many options to define it either, with the story pretty much railing us into some semi-optional "die a legend" claptrap that sends V off to do a completely idiotic job with a bunch of misfits and zero chance of success. Then that horrendous Heist nonsense is over and V has one clearly defined goal: Survival.
And that is a goal we don't actually get any chance whatsoever to reach, because there's just no path to that outcome. It doesn't matter what we do. Either V dies before that point or V ends up getting soulkilled. The end. It must happen and while there's a million choices along the way that one might have wanted to make, we do not get to do so because CDPR made that choice for us and put the story on rails to get to that point.
Further, the way the story works, there's really no change to the world if V had never been born or had died before making it to Night City. Except dying before the six month montage with Jackie would have been easier on all the friends V makes in and around NC, probably.
And that is why the story in this game turns into despair. Calling it bleak or something to that effect is actually an understatement. A bleak situation can still be resolved. Bleakness does not necessitate despair, the feeling that any struggle has ceased to serve any point.
If you've somehow fallen out of an airplane without a parachute and you're dropping a few miles for a splash in the middle of the ocean then you're done. Landing in water from that altitude is fatal and there are no soft spots in the middle of the ocean. And even if you somehow miraculously survived with a million broken bones, you'd be in the middle of an ocean, drowning. You can scream, you can wave your arms about, you can wet yourself. All of those are equally good options that won't change a thing, because you're done. Game over. This is despair.
But if you're inside a plane that is going to crash somewhere then you're not entirely dead yet. There is some chance. The situation is grim as hell, you will probably die, but you have not quite died yet. May as well keep your eyes open and hope an opportunity will present itself. Chances might be low, whatever you can might be one ridiculous long shot but a long shot is infinitely more likely to work than no shot.
Working those long shots is often what the Cyberpunk genre is about. That those long shots are low percentage but still a shot, that everything looks very dark and invites despair but actually there's still something to struggle for. You are not dead until you're dead, and it doesn't matter what everybody else is thinking, it doesn't matter that it makes no sense, because there is still something you can do. One foot in front of the other, seeking out that nearly hopeless long shot.
But in this game, that's just not true. There is literally no shot. You don't get to have a chance. You do not get to fight for it. You are being plot dumped a few miles above the middle of the ocean without a chute. Make your peace with it. Or don't. Die with clean underwear, in a way that would make Geralt proud, or don't. Whatever. And that really sucks. There's no meaning to V, no meaning to V's life, and not really any meaning to V's death either. Does anyone remember the