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If you have been bitten by the Bioshock 2 crash-after-intro bug, there's a better way to solve the problem than changing your save-game folder or deleting all your saves. You can keep your old save games!

It seems like the thing that causes this bug is the quicksave in particular getting corrupted. All you need to do is delete the quicksave files (mine were named "qs9.bsb" and "qs9.bsh") and the game will launch just fine. (There's also a directory for your quicksave, which I just ignored, but the fix worked nevertheless.) Whatever your quicksave file is named, it should be pretty clear both by the date-modified and by the naming convention for the autosaves and the "real" saves being pretty clear.

(My save games live in C:\Users\[username]\Documents\Bioshock2\SaveGames on Windows 10.)

Of course, you'll lose your quicksave this way. If you're doing proper saves along the way, though, you shouldn't lose too much progress!

Good luck out there, folks.
Post edited January 27, 2021 by wazroth