It might not have writing as good as other entries in the series, and has a bit less soul in some areas, but it's still a blast to play.
Out of the modern Fallout games, it has the best gunplay, although the melee system is arguably a sidegrade from 3 and New Vegas (insert countless instances of accidentally using a grenade while trying to melee power attack here). There's a good amount of memorable companions to choose from, with at least some of them having their own unique quest. The skillpoint system is ditched in favor for a much more dynamic perk system (Like 3 and New Vegas, but there's a metric ton to choose from, and you get them every level), and unlike Skyrim, they didn't get rid of primary stats, they are in fact, required in higher levels to get higher leveled perks.
Power armor actually feels like power armor this time, instead of just bulky armor that has a higher armor stat. It's customizable with better parts and mods, such as a jet pack. The game also has the best main menu in the series, mainly for the music, "Heroic Shinra Theme" is very inspiring. Weapons are customizable, there's a junk scrapping system for parts, and a settlement building mechanic.
One of my favorite ways to make caps, is to found a bunch of settlements that produce clean water, then sell a ton of bottled water to merchants at exorbitant prices. I call it the "Bottled Water Scam". Then on the side I grow a bunch of crops, to cook with, and gain a galaxy brain from all the exp I get from cooking them, especially with a high intelligence stat.
Also, the default male protagonist kinda looks like a younger Brendan Fraser.