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www.mobygames.com/game/chemicus-journey-to-the-other-sideMyst-like science adventure requires kids to use chemistry to solve a series of puzzles to rescue a kidnapped friend. The game is very well done, but difficult-- you may need to refer to the PDF help file found on the CD. Content addresses substances (their properties and transformations), atom structure, chemical bonding, electrochemistry, organic chemistry and more. The puzzles get kids to use the Periodic Table of Elements, conduct experiments, calculate reaction equations and work with formulas.