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Klumpen0815: Hmm, no chance in WINE then as it seems.
I'm on the fence of buying, since I still got a working WinXP partition with a licence that came with this PC.
Are you using the latest version of Wine? I've ran two XNA 4.0/.NET 4.0 games successfully (Sword of the Stars: The Pit and Dungeonmans) under Wine 1.8-rc2 or later.