RonnyRulz: I finally fixed this. Loading screen audio was incredibly soft. Voices were a huge problem. I knew the problem was surround sound settings / center speaker issues - but I have a Digital Optical connection to a stereo setup. Witcher 3, for whatever reason, was sending a bad audio signal.
-=My System=-
Setup: Klipsch 20B soundbar connected via Digital Optical cable to MOBO audio ( Realtek ALC1150 )
My soundbar has Dolby Digital encoding in it, but the problem was it wasn't receiving Dolby Digital from the source (PC). My audio driver that came with my MOBO failed me in this regard, so I installed an unlocked version that DOES allow Dolby Digital. So now it sends the correct Dolby Digital signal to my (stereo) soundbar. The center speaker is no longer missing.
-=The Fix=-
Install unlocked Realtek Audio Drivers. Also applied the "Surround Sound Fix" for windows.
-==The Relevant Links==-
Unlocked Realtek Driver:
https://www.techpowerup.com/forums/threads/unlocked-realtek-hd-audio-drivers-windows-7-8-10-with-dolby-digital-live-and-dts-interactive.193148/
Surround Sound Windows Fix:
https://www.reddit.com/r/witcher/comments/36h29c/surround_sound_51/crevdwh/
-=Making It Easy On You=-
I made my own instructions/package for everything. One-stop solution for anyone to download if they want things easier. If you don't trust my package, just download everything through the above Relevant Links.
It's short, easy, and simple. Uninstall old audio drivers, install new ones, change to test mode & sign dll, & copy/paste unlocked dll.
https://www.dropbox.com/s/1tc4vsb0rz728og/Witcher%203%20low%20audio%20fix%204%20Digital%20Optical%20connection%204%20Windows%207%2C8%2C%20%26%2010.zip?dl=0 Duuuude, you just made my day. Fixed and working great. Love ya.