Found this little nugget there if anyone cares.... seems to originated on Gamespot.


I CANNOT STRESS ENOUGH DO NOT USE MUTAGENS UNTIL YOU HAVE BOTH GREATER AND 2 IN IMPREGNATION

Training tree 6 points (why because its mandatory... sigh)

0 Hardiness - Why because 10-50 vit is useless compared
1
Dagger Throwing - Why because a quest requires this... get 2 if you
want to use quen or want to play hard/insane (throwing daggers chews
most bosses down)
0 Vigor Regen - Why because its the least of the useless skills...
1
Parrying - Why because you want mutable skills, and this is a prereq...
get 2 if you don't plan to ever cast quen or you want to play
hard/insane
1 Arrow Redirection - Why because its mutable
2 Fortitude - Why because its mutable and one extra vigor means a lot

Leaving you with a choice to get 2 in parrying or 2 in dagger throwing

after level 7 go to

Alchemy
1 Synthesis
1 Spec: Pot
1 Harvester
1 Spec: Oil
2 Impreg (35% boost to 10 mutagens is what it says, in effect it doubles all mutagens)
1 Taster
1 Metathesis mutable
1 Condensation mutable
1 Beserker mutable
1 Mutant mutable
1 Amplification mutable

after level 19 go into

Swordsmanship

1 Position - Pre-req
1 Violence - Pre-req
1 Whirl - Pre-req
1 Hardy - Pre-req
1 Finesse - Pre-req
1 Invincible - mutable
1 Combat acumen - mutable
1 Whirlwind - mutable

This unlocks 10 mutations by level 28

after level 27 you can choose, dependant on your mutations choice

If you choose Critical Mutagens get 10 x 6% = 60% base critical effect + bonus from skills

2 Finesse
2 Whirlwind

and have 100%+ base chance to inflict any critical with an attack... this is the MOST powerful sword based killing tree

And you are free to take whatever from 29 on... you basically instantly kill any human and cripple any monster

If you choose Power Mutagens
get 10 x 3 min and 10 x 6 max damage for 30-60 bonus damage (basically
like having the best weapon in the game doubled) + bonus from skills
mauling any enemy you hit with ease

2 Violence
2 Whirl
2 Percision
2 combat acumen

And you are free to take whatever from 32 on... you basically deal some INSANE damage per hit

If you choose Strength mutagens
get 10 x 4 armor + 10 x 1 vitality regen for 40 base armor and 10 base
vitality regen + bonus from skills... makes you basically invincible to
anything

2 Tough guy
2 Invincible
2 Combat acumen

And you are free to take whatever from 31 on... you basically a walking tank that can take any beating in the game...
Sudden Death - a good skill to take with the armor build as it will allow you to kill somewhat faster

Mutagen List
Vitality is +10
Critical is 3% to all (directly stacks on each other)
Power is 1-3 to sword damage
Strength is 2 armor and +1 vitality regeneration
Concentration does not appear to come in a greater format...
Range is does not appear to come in a greater format...
Enhancement is 5% bonus adrenaline on hit

AFTER level 2 impregnation you get... ALWAYS get impregnation BEFORE using ANY mutagens... ALWAYS

Vitality is +20
Critical is 6% to all
Power is 3-6 to sword damage
Strength is 4 armor and +1 vitality regeneration
Concentration does not appear to come in a greater format...
Range is does not appear to come in a greater format...
Enhancement is 10% bonus adrenaline on hit

They come in 3 levels
Lesser
Normal
Greater

Always use greater... ALWAYS

Sword Enhancements
Various runes, the best of which is the +7% damage +8% bleeding one
Armor Enchancements
Unless you are a mage any +2 armor one is good... the other effects don't matter enough
If
you are a mage one unique armor one gives +5 to sign damage, and the
Wraps at the end of the game give +3 (both have +2 armor as well)

Best
Swords seem to be the one forged from the gargoyle quest (act 3) and
the silver sword found in the chest from the gargoyle quest (act 3)

Best Armor seems to be the one you can buy in Act 3
Best
leggings / gloves seem to be forged ones, but they don't really matter
much, best leggings I found gave 3 armor, best glove 2 armor (and
sometimes the Act 3 humans drop nice things!)

Best Trophy
Troll +9 damage
Arachnid thing +8 armor
One of the boss monsters +5 armor +55 vitality and + something else

Abilities
Axii Sign Hex : - Unlocked in dialogue - Goes from level 1 - 3
Intimidate: - Unlocked in dialogue - Goes from level 1 - 3
Persuasion - unlocked in dialogue - Goes from level 1 - 3
Cover:
damage reduction +10% - Unlocked by being under Triss's 'arrow to
butterfly' spell and not leaving it - RIght at the start of act 1 (not
the prologue) - Stays at level 1
Strong Back : +50 to capacity
- You need to spare the guard captain in the prologue and then in the
jail you carry him to the exit of the Dungeons of La Valettes - Stays at
level 1
Conjuror : +3 sign damage - fail a axii cast, or use a
lot of magic - Mine stayed at level 1, but I didn't cast spells, I
assume it goes to level 3
Assassin : +25% damage when
attacking from behind - Find the white cloaked body in a haystack in the
town fight very early on - Stays at level 1
Haggling : -20% to cost of shops - Successfully haggle down the merchant for the problem at the docks - Stays at level 1
Strong Stomach : 10% resistance to being poisoned - make and consuming a potion in a certain act 1 boss fight) - Stays at level 1
Thrower
Act 1 increases thrown weapon damage by +5 - requires dagger throwing -
and then beat the guys in the 'party' quest at throwing things... I
think it stays at level 1
Birdman +10% damage to harpies - Kill the harpy queen - Stays at level 1
Anatomy Lesson +10% damage to humans - Checking the bodies in act 2 with the surgical equipment and recover the metal shard - Stays at level 1
Child of the night +2 vitality regen at night - sneak through the camp undetected near the end of act 2 - Stays at level 1
Arcane Knowledge
+0.5 to all sign intensity - Either part of the gargoyle quest of act 3
or from reading every book in the game - stays at level 1

not confirmed

Giant (+10% to giants, from doing the human act 2 and killing the golem)
Immolation (+10% fire resist, keep stumbling into camp fires in act 2)

dagger throwing is the most useless skill of the game. you shouldn't spend a point on it. there are cool skills on alchemy tree that gives extra effects.

Because maybe that's the way he wants to play it. Some people enjoy building characters according to stat sheets so they can have an "optimal" character. There's nothing wrong with that :)

is it just me or is the whole thing gibberish ?

maybe in his own head it makes sense,but i cant find a single useful thing that is explained properly.
then again i never was a spreadsheeter ;)