Sundered is also another game with a not widely known Mythos setting, and the final boss is one of the Elders (or the last remnants of your humanity, depending on the path you chose through the game)
sqlrob: Agreed on Cultist Simulator. I need to go back to that, I haven't played in a while. Maybe now's a good time, being close to Halloween.
Why Phoenix Point? I always thought of that as an X-Com clone, does it veer into Mythos? It is something I want to play, I just have a huge pile in front of it.
It has a quite Lovecraftian setting, although there's no direct reference to the Mythos until the ending of the game, where you discover the *SPOILER REDACTED* origin of the Pandoravirus.