Zoltan999: Are you just trying to save installation space on your portable device this way? Reason I am asking, (and I am sure you've considered this, but...) I have just used a usb to transfer save and possibly profile files from my desktop, and downloaded them to my laptop when travelling. Of course this requires you to install the full game on all devices you plan on playing it. Also, I should think, that even if successful in running games like Witcher 3 and NMS from a storage device, there would possibly be real slowdowns and stuttering in play that way?
Well, I'm planning on keeping the full game on the USB and then transferring the files over to the computer so that I don't have to deal with slowdowns. But because everything is in one folder, saves included, it makes it easy to transfer everywhere.
nightcraw1er.488: I would say you have pretty much no chance of running something like Witcher 3 off USB at the moment. It requires a shedload of computer power, loading textures, processing and such like. Even if you were to get it running on USB you would notice a fair bit of a performance drop, even if it was just down to the read speed of the USB stick, although theoretically USB 3.1 might just be able to compete with HDD speed.
As a secondary, I would imagine that you would need C++ extensions, physx, and other drivers also installed on the drive, plus all the reg-entries.
Why do you need to out of interest, is it to play on multiple machines?
Well to address the first comment, I would really just keep the entire game files on the USB in a folder and then transfer that folder to the device I'm playing and run it off their. This way, I don't deal with slowdowns.
However, my main concerns is my progress. I want to keep everything in a folder and USB so that I can easily take my game, and it's progress, on the go and use it across the systems that I'm using at the time.
Since I'm constantly around because of the nature of my work, I would like to make some progress on my laptop and then transfer my progress to my home PC when I get back and play it on the best quality.