I have tried to run the exe file in different compatibility modes ran as administrator, made an exception in DEP for the games exe files, verified the fles with the GOG, installed DX 10 and nothing works.

Spesifications are:

MSI GAMING PRO CARBON mobo

32gb if Corsair LPX 3000 mhz ram

EVGA SC2 GTX 1080TI 11gb vram

Windows 10 OS.

ANYONE that can solve this problem ?

You generally have to reboot to make DEP settings take effect.