Chief_Ug: I upgraded from Windows 8.1 to Windows 10 and haven't had any issues with SC. Interestingly enough, FC stopped working for me until I installed Galaxy, and now both are fine again.
Just a heads up though... be sure to back up your saved games directory. The Win10 upgrade process has been known to kill or move some such directories. I got a big scare at first, with all my saved games deleted. Fortunately I ended up finding them on a different path.
auroraparadox: Thanks for the response. I haven't installed Galaxy yet. I wanted to give GOG more time to polish the program.
What graphics card is your system using and have you run into any glitches while playing the game? I heard the latest patch prevented the game from starting.
I've read some people having problems, but I've been just fine with the patch. I noticed a bit of glitches, but they were not fatal, just small lack of polish that will surely be fixed eventually. Stuff like menu textboxes looking weird and texts being a bit off. Running a Geforce GTX 770. I had the game crash once, and of course that was after a long series of end-of-chapter boss battles, before being able to save >_<