Zadok_Allen: Dragonfall features one paid run that requires a Decker. It can be skipped, but you'd lose so much money: You'd need to save a lot of money (~10k) ahead of time to proceed with the main campaign. It is the best paid run. Been there, done that. Grave disadvantage, but possible.
Contrary to DalekSec's post the Trial Run does not require decking, it only offers a few extra options if you bring decking (as do most runs really). Glory's run does not need decking either.
Hong Kong has one unskippable run that requires decking, so it can't be finished w/o a Decker. I managed with Decking 3, which made it the hardest run of the main campaign. Decking 5 should do the trick though (as does a decker NPC).
I don't said that you need decking to complete those two runs. What I said, is that without decking, you cannot get the paydata in any of the two runs.