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If you encountered a problem with loading save games after the latest patch, hotfix is now available.
File can be downloaded from Library -> Pillars of Eternity, like any other patch.

It's a small ZIP file, please unpack it to the main game folder, overwriting all files when prompted.

If problem still persists after that, please post here and/or contact Support.
If you have White March, did you use additional patches for DLCs as well?