So what if I prefer blonds over mammoths. I chose to quit from the eon program. The result was instant, back to main menu followed by a freeze and a pop up.

ErrorLog0001.txt
General Info
------------
Application : Owarogl_sgui
Version : 3.0.8.246

ModName :
ModDir :
ModVer : (0.0)

ErrorType : Unknown
ErrorText : SAIL function "SetAchievement" : Unable to write to E:\GOG\Original War\UserProfiles\normal\Default\customsettings.ini

Stack : 0042C1B1 OwarOGL_SGUI.exe
Stack : 0042BDD9 OwarOGL_SGUI.exe
Stack : 00511A35 OwarOGL_SGUI.exe SCustomSettings (92 - 65)
Stack : 10004F8B Lua.dll

Module : 00400000 - 046CFFFF OwarOGL_SGUI.exe
Module : 046E0000 - 046EDFFF LuaLib.dll
Module : 04CB0000 - 04CE1FFF libtheora.dll
Module : 067C0000 - 067D8FFF OpenAL32.dll
Module : 06820000 - 06A78FFF RTSSHooks.dll
Module : 075A0000 - 079F7FFF wrap_oal.dll
Module : 07B30000 - 07B39FFF VidUtil.dll
Module : 07B50000 - 07B5BFFF 4xm_sdk.dll
Module : 10000000 - 10013FFF Lua.dll
Module : 152D0000 - 152E2FFF OWSteam.dll
Module : 51ED0000 - 51FCEFFF OpenGL32.dll
Module : 51FD0000 - 520FAFFF libvorbis.dll
Module : 573E0000 - 57411FFF steam_api.dll
Module : 57420000 - 57459FFF wdmaud.drv
Module : 57490000 - 574CEFFF GLU32.dll
Module : 576F0000 - 5780DFFF AUDIOSES.DLL
Module : 57E30000 - 57E3EFFF resourcepolicyclient.dll
Module : 57E50000 - 57E71FFF MSVFW32.dll
Module : 57E80000 - 57E9AFFF AVIFIL32.DLL
Module : 57EA0000 - 57EBEFFF libvorbisfile.dll
Module : 57EE0000 - 57EE7FFF midimap.dll
Module : 57EF0000 - 57EF9FFF msacm32.drv
Module : 57F00000 - 57F08FFF libogg.dll
Module : 57F10000 - 57F17FFF wsock32.dll
Module : 58260000 - 58266FFF ksuser.dll
Module : 58300000 - 58307FFF AVRT.dll
Module : 58320000 - 58338FFF MSACM32.dll
Module : 589C0000 - 58BCEFFF nvspcap.dll
Module : 5C710000 - 5C80FFFF Windows.UI.dll
Module : 5CAC0000 - 5CB21FFF MMDevAPI.DLL
Module : 5CB30000 - 5CB73FFF WINSTA.dll
Module : 65A40000 - 65ABDFFF DSound.dll
Module : 6A210000 - 6A293FFF TextInputFramework.dll
Module : 6BF60000 - 6C188FFF iertutil.dll
Module : 6C340000 - 6C59DFFF CoreUIComponents.dll
Module : 6C5A0000 - 6C628FFF CoreMessaging.dll
Module : 6C630000 - 6C709FFF wintypes.dll
Module : 6C710000 - 6C7D1FFF InputHost.dll
Module : 6D2E0000 - 6D2F8FFF dxcore.dll
Module : 6D980000 - 6D9A2FFF DEVOBJ.dll
Module : 6E070000 - 6E112FFF MSVCR90.dll
Module : 6E500000 - 6E58CFFF comctl32.dll
Module : 6E5E0000 - 6E67EFFF apphelp.dll
Module : 70C30000 - 70C58FFF ntmarta.dll
Module : 72B50000 - 72B5EFFF WTSAPI32.dll
Module : 72D30000 - 72D54FFF dwmapi.dll
Module : 73370000 - 733E9FFF uxtheme.dll
Module : 734C0000 - 734E2FFF winmmbase.dll
Module : 734F0000 - 73513FFF WINMM.dll
Module : 73520000 - 735E5FFF PROPSYS.dll
Module : 736B0000 - 736B7FFF version.dll
Module : 749E0000 - 74E3AFFF wininet.dll
Module : 74F50000 - 74F59FFF CRYPTBASE.dll
Module : 74F60000 - 74F7FFFF SspiCli.dll
Module : 74F80000 - 74F8DFFF MSASN1.dll
Module : 74F90000 - 753D8FFF SETUPAPI.dll
Module : 753F0000 - 75414FFF IMM32.DLL
Module : 75420000 - 75465FFF WINTRUST.dll
Module : 75470000 - 754B3FFF shlwapi.dll
Module : 75520000 - 75A98FFF shell32.dll
Module : 75AA0000 - 75C36FFF user32.dll
Module : 75C40000 - 75D9AFFF gdi32full.dll
Module : 75DA0000 - 75DB6FFF win32u.dll
Module : 75F40000 - 75F7AFFF cfgmgr32.dll
Module : 75F80000 - 75F98FFF bcrypt.dll
Module : 75FA0000 - 75FE2FFF powrprof.dll
Module : 76050000 - 760AEFFF bcryptPrimitives.dll
Module : 760B0000 - 7616AFFF RPCRT4.dll
Module : 76170000 - 7617CFFF UMPDC.dll
Module : 76180000 - 76192FFF cryptsp.dll
Module : 761A0000 - 761BAFFF profapi.dll
Module : 761C0000 - 76251FFF oleaut32.dll
Module : 76260000 - 762D5FFF sechost.dll
Module : 762E0000 - 7639EFFF msvcrt.dll
Module : 76470000 - 764EBFFF msvcp_win.dll
Module : 764F0000 - 765EAFFF CRYPT32.dll
Module : 76680000 - 7675FFFF KERNEL32.DLL
Module : 76760000 - 76D25FFF windows.storage.dll
Module : 76D30000 - 76D8DFFF WS2_32.dll
Module : 76D90000 - 76E92FFF MSCTF.dll
Module : 76F00000 - 76F0EFFF kernel.appcore.dll
Module : 76F10000 - 76F8FFFF clbcatq.dll
Module : 76F90000 - 77008FFF advapi32.dll
Module : 77010000 - 77093FFF shcore.dll
Module : 770A0000 - 77314FFF combase.dll
Module : 77320000 - 7743EFFF ucrtbase.dll
Module : 77440000 - 77445FFF psapi.dll
Module : 77450000 - 77470FFF GDI32.dll
Module : 77480000 - 7767DFFF KERNELBASE.dll
Module : 77680000 - 77776FFF ole32.dll
Module : 77790000 - 77929FFF ntdll.dll
Module : 785E0000 - 7A2A4FFF nvoglv32.dll
Module : 7C340000 - 7C395FFF MSVCR71.dll

Params :
ParamCount : 0

Game Info
---------
Multiplayer : False
Multi.GameState : Undef
Multi.ChatConnLost : False
Multi.IAMServer : False
Multi.Joined : False
Multi.Loaded : False
Multi.MapVersion : 0
Multi.OffLine : False
Multi.OnLine : False
Multi.ServerLost : False
Multi.StatusText :
MultiDef.MapName :

mission_number : 1
mission_campaign : 1
camp_names[mission_campaign] : Am
mission_names[mission_number] : 01
game_difficulty : 2
ingame_video : True
stop_talking : False
stop_action : False
end_of_mission : 0
end_the_mission_allowed : False
dialogue_skipped : False
last_title_ident : -1
last_title_unit : 17
last_title_radio : False
last_title : We got less betwen our legs than you, but a hell of a lot more between the ears Sikorski.

lastSail : 2456
tick : 7024

Random Stuff
------------
GodMode : False
DeveloperMode : False
ModCBMode : True
OfficialMod : False
InterfSide : 1
MultiCore : True

Windows Info
------------
Product : Windows 10
Win32MajorVersion : 10
Win32MinorVersion : 0
BuildNumber : 9200
ServicePack :
ServicePackMajor : 0
ServicePackMinor : 0

Physical Memory : 16375MB
CPU Name : Intel(R) Xeon(R) CPU X5675 @ 3.07GHz
CPU Clock : 4229Mhz
Current CPU Clock : 4232Mhz

==================================

NOTES:
An error log was shipped with the game by the way, from a windows vista SP2 machine running an AMD Phenom(tm) 9650 Quad-Core Processor

Does that directory location exist on your computer? It should be creating the directory. You may need to run OW with Admin rights (Though it shouldn't be nessisary). Other than another application having the customsettings.ini file open (And thus blocking all writes to the file) you shouldn't be able to get that error.

Yes it does exist however I'm not using the default profile, I renamed it. But when starting the game, I'm always on the Default profile.

Odd. If you run the game with admin mode (Right click on OwarOGL_SGUI.exe and goto properties and then compatibility tab. Then check the checkbox for "Run this program as an administrator") does it load the last used profile (You may need to go into OW, select the profile, exit and then re-launch to check).

OW is still using the registry to set and get the last profile (Though it shouldn't require admin rights to access).